Intriguing peri-strut low-intensity area detected by optical coherence tomography after coronary stent deployment.
نویسندگان
چکیده
BACKGROUND Although peri-strut low-intensity area (PLIA) is frequently observed on post-stenting optical coherence tomography (OCT) images, the histology associated with PLIA is undocumented. METHODS AND RESULTS The 36 porcine coronary lesions treated with bare-metal (BMS: n=16) or drug-eluting (DES: n=20) stents were assessed by OCT and histology at 28 days. DES showed a significantly higher incidence of PLIA than BMS. Also, +PLIA stents had greater neointima than PLIA stents. Histological analysis revealed the existence of fibrinoid and proteoglycans at the site of PLIA. CONCLUSIONS PLIA might be represented by the presence of fibrinoid and proteoglycans, and associated with neointimal proliferation after stenting.
منابع مشابه
Clinical Characteristics and Prognosis of Peri-strut Low-intensity Area Detected by Optical Coherence Tomography
BACKGROUND Peri-strut low-intensity area (PLIA) is a typical image pattern of neointima detected by optical coherence tomography (OCT) after stent implantation. However, few studies evaluated the predictors and prognosis of the PLIA; therefore, we aimed to explore the genesis and prognosis of PLIA detected by OCT in this study. METHODS Patients presenting neointimal hyperplasia documented by ...
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عنوان ژورنال:
- Circulation journal : official journal of the Japanese Circulation Society
دوره 74 6 شماره
صفحات -
تاریخ انتشار 2010